I think it's hypocritical to be opposed to the running clock - and in the same breath, criticize coaches for "running up the score". So basically what you're saying is - you want to play the full game with stoppages but you want one team to stop playing/play hard.
So just to be clear, we don't want to take minutes and seconds away from players on the losing team, but we want to ask the players on the winning team to not play hard or to their fullest potential? I don't see this as being fair either.
Also - MOST of the time, in these blowout situations, the team that is winning switches to a motion offense where they pass and cut and throw the ball around for minutes at a time. I ask, how is this making anyone better on either team? Both teams at this point, are "going through the motions." If a player goes to practice and just "goes through the motions" are they getting better? Most people would say no, that you need to practice hard to get better. If that's the case, then why are we ok with it happening in games?