It's absolutely a benefit to the league overall. Both teams got wins in week 2, rather than one of them getting a loss. This means more computer points for anyone who is able to beat them later in the conference slate. This means a higher chance that more MAC teams play home games in the playoffs.
If Versailles played Coldwater in week 2, they're, in all likelihood, 1-2 at this point in the season. Is it not better for Versailles to be 2-1 and many believing they're a State Championship contender than to be at 1-2?
Also, you could argue the reason Versailles is better over the course of the past few years is because they've benefitted as much as anyone from not having to play someone better than them in week 2, and taking a loss. We can pretend that there is no difference between 2-8 and 1-9 or 3-7 and 4-6, but there is. The MAC absolutely, unequivocally benefits from not playing all other opponents.
Is it a shame that two of top 3 teams in the conference won't play this year? Sure it is. But to say as a whole it doesn't benefit the league overall is incorrect.