maple, they are much improved from when your truckers with multiple D1 guys on the team played them.
I think they can make some noise, but aren't a favorite quite yet.
I'd look for Mentor Lake to rebound, I assume Ursuline will be excellent again as Reardon will find guys to bring in. VASJ will be good, but with the transfers everyone mentions there, will they bump to D3? Canton South and Perry will be solid in region 13 as well
Region 14 is a gauntlet. VW would be a solid choice to make it back to the regional final. Clyde loses a lot, Bellevue loses a good amout as does shelby. Bellevue and Clyde are great programs though who can contend for a regional title most years. Wauseon can also be a dark horse type team and Keystone will have a couple solid players, their schedule is terribly weak though.
If Hartley is back in division 4, I like them as the favorite. As someone mentioned, they have had a ton of success in D4 and I would think that would continue. BC loses quite a bit and will have a coaching change. St. Clairsville and IV are usually always solid in that region as well.
Finally in region 16, the usual suspects, Wyoming, Mcnick, Massie, and as someone said, Milton Union will be interesting to watch as well. I don't know what Eaton and Waverly have back, but if memory serves me, they were good last year too. What about Indian Hill?
D4 has been a pretty fun division and great for public schools. Unless more privates find their way back into d4 and reassert dominance.