I'll take a shot at predictions on the NE Ohio side:
D1 R1
St Edward vs. Canton McKinley (Brunswick)
Medina vs. Cleveland Heights (Byers Field)
D2 R5
Walsh Jesuit vs Hudson (Twinsburg or Macedonia)
Hoban vs Riverside (Macedonia or Solon)
D3 R9
Chardon vs Aurora (Solon)
Ursuline vs VASJ (Mentor)
D3 R10
Tiffin Columbian vs Buckeye (Sandusky)
D4 R13
Lake Catholic vs Struthers (Ravenna, Solon, Macedonia or Hudson)
Canton South vs West Branch (Perry or Marlington)
D4 R14
Shelby vs Glenville (Medina or Ashland)
D5 R17
Kirtland vs Independence (Bedford)
South Range vs Clearview (Strongsville, Berkshire or Niles)
D6 R21
Mogadore vs Mineral Ridge (Ravenna or Salem)