We've got some odd regionals this year IMO. We have one highly competitive regional and three others with clear cut favorites IMO. Since I said this, I'm sure things will get completely jacked up.
Hands down the most competitive is Louisville with Tiffin Calvert, Warren Kennedy, Hillsdale and Lake Center. Any of the four could win it and i'd not be surprised. I still don't get sending Tiffin Calvert that far East but they've done that for 7 of their 8 regional appearances. TC and JFK have been there the last four years, Hillsdale three times and LC now twice in a row. Calvert is still super young - most of their lineup is sophomores (although as freshman they won 30 games) but has veteran pitching (this will be JR Blake Coleman's third regional start). They def. miss the two seniors from last year in the batting lineup. Lake Center has put up big numbers, but was shutout by Hiland in the regular season in their biggest game. I think Hillsdale battles them.
I'd expect Leipsic to come out of NW Ohio. My guess is they meet Ft. Recovery in the final. Again, not an overly strong regional.
Hiland is far and away the favorite in the Lancaster regional. As stated above, anything can happen but I think there's a serious talent and experience gap.
Northmor and Russia are the two best teams there but will meet in the semi-final. I'd still expect Russia to win this one.