bob99
Well-known member
No problem my horse's--- friend. You jump first and I will be right behind you. Trust meLet's find you a high cliff, Neanderthal Icarus.
No problem my horse's--- friend. You jump first and I will be right behind you. Trust meLet's find you a high cliff, Neanderthal Icarus.
Posting messages on here that were intended for yourself again?Maybe you should not tell people they need help when they do not. My God, the arrogance oozes out of you.
Well one guess would be that Biden was pumped up on Adderall or some other amphetamine. There is clinical data supporting the off label use of these agents for early stages of dementia especially if the goal is to temporarily enhance cognition and change characteristics of the individuals personality for short periods of time.
Study Suggests ADHD Drugs Could Treat Alzheimer’s Symptoms
Researchers have discovered that medications approved to treat ADHD may also help with symptoms of Alzheimer’s disease.www.verywellhealth.com
An analysis published in the Journal of Neurology Neurosurgery & Psychiatry reviewed 19 clinical trials on the use of noradrenergic drugs—often used to treat anxiety, depression, and ADHD—in people with neurodegenerative disease.1
Researchers found that these drugs can improve general cognitive performance and apathy, the most common neuropsychiatric symptom in Alzheimer’s patients.
Some experts like Dr. Carole Lieberman (forensic psychiatrist) observed: “If you look at how Joe Biden usually is — slow and stumbling — compared to how he was during the State of the Union — fiery and angry — these are signs that are typical for someone taking Adderall or any amphetamine,” she said. Dr. Lieberman, who has not personally examined the president, said the signs of potential pharmaceutical use go beyond how Mr. Biden spoke during the nearly 90-minute speech, but also in his mannerisms.
Where did you get this idea from? There are many products that act as disinfectants via an antimicrobial MOA? It's not unusual for antimicrobial compounds to work in both in vivo & ex vivo testing. Alcohol as a skin/wound disinfectant would be one example.
In fact the normal research progression is to first test new chemicals/chemical mixtures in vitro then progress to ex vivo then in vivo and finally in clinical (drug) & real world (surface disinfectant) testing.
So now you've moved the goal posts to a discussion of the relative efficacy of various antimicrobial based disinfectants?Uh, what? If you are using alcohol as a wound disinfectant, you should probably stop. This is a great example proving my point. Alcohol is a decent disinfectant (not great but pretty good) for using on inert surfaces and intact skin. It is not a good agent for open wounds and certainly doesn't have anti-microbial action systemically.
And you would know the dosing regimens Biden's doctors may be using with these agents? It's my impression that they will do anything to prop up the POTUS so he can perform in front of the public.You might want to read the study that is referenced in that post if this is your explanation of a supposed change in Biden's cognition on Thursday night. It is a well done systematic review and worth looking at, but it doesn't say or suggest anything like what Carole Lieberman or you are saying. The review evaluates chronic treatment of Alzheimer's with noradrenergics and finds that after weeks ok a treatment there may be a small benefit in MMSE performance. It does not suggest that you can load someone up with a drug an improve their cognition. In fact, it specifically excluded studies that could test such a hypothesis.
And you would know the dosing regimens Biden's doctors may be using with these agents? It's my impression that they will do anything to prop up the POTUS so he can perform in front of the public.
You are aware of the concept of "off label" drug use aren't you? The information provided in the review would enable Biden's doctors to ethically experiment with Adderall and other amphetamines as dementia treatment options. Not saying they are doing this but a lot of people knowledgeable in the effect of these drugs said it sure looked like they were.
BTW, it's interesting to see how with the drugs no longer being used (assuming they were used Thursday night) that Biden has reverted to his pre-SOTU speech cognitive failings as he hit the campaign trial on Friday.
That Biden had been medicated during the speech was supported by Biden's glitchiness the following day. His campaign speech in Philadelphia, Pennsylvania, which was a slightly repackaged version of his State of the Union speech, was a hot mess. At one point, he declared, "Pennsylvania, I have a message for you: send me to Congress!"
Even on his favorite topic, the Capitol riot, Biden stumbled, erroneously referring to the date as "July the 6th." Considering he's been obsessing on this subject for three years, it's a big deal that he messed it up. Another notable flub came when he said that every world leader has conveyed to him, "You can't win again." While, technically, polls show this is correct, I don't think the story accurately represents what Biden intended to say. Another embarrassing moment was when he forgot the name of the Federal Reserve.
So now you've moved the goal posts to a discussion of the relative efficacy of various antimicrobial based disinfectants?
BTW using alcohol on "intact skin" would be a fine example of it's clinical use as an in vivo disinfectant. As you are probably aware your intact skin is part of your body. And did you know that your biggest organ is your skin? And if you were lost in the jungle with nothing but a bottle of very expensive tequila and you suffered a severe abrasion you would be foolish not to thoroughly wash the wound with that bottle of tequila before putting on any bandage.
How do drug delivering skin patches work?What? Use of alcohol on intact skin isn't in vivo. The outer lay of skin is not alive and serves as a barrier to things like alcohol getting to the live tissue. That's the point of skin.
What we're suggesting is that Biden suffers from the early stages of dementia and that to make him presentable to the public he is dosed with various drugs and cocktails of drugs with Adderall and other amphetamines being likely candidates.The dosing regimen is not relevant. What you and MAGA seem to be suggesting is that he has dementia, was given some cocktail of drugs and instantly improved so that he could give a speech, was taken off the drugs and then the next day had reverted to baseline. That notion is absurd. There aren't any drugs that would work that way and nothing that you have posted gives any credence to that being possible. It's not. The idea is ridiculous.
Because a liberal Democrat says so?The dosing regimen is not relevant. What you and MAGA seem to be suggesting is that he has dementia, was given some cocktail of drugs and instantly improved so that he could give a speech, was taken off the drugs and then the next day had reverted to baseline. That notion is absurd. There aren't any drugs that would work that way and nothing that you have posted gives any credence to that being possible. It's not. The idea is ridiculous.
How do drug delivering skin patches work?
If I'm developing a topical health care product that moistens skin this is how I would describe a simplified version of the testing flow:
* In vitro (lab) testing to identify the basic hydration properties of the active agents used in the product. This could include artifical skin and skin cultures.
* Ex vivo testing on excised skin.
* In vivo testing on people
* Controlled clinical testing on the final product.
What we're suggesting is that Biden suffers from the early stages of dementia and that to make him presentable to the public he is dosed with various drugs and cocktails of drugs with Adderall and other amphetamines being likely candidates.
Of course we don't know this for sure as I haven't seen testing proving whether Biden does or does not have early stage dementia nor do I know that he's definitely taking these drugs. But those who specialize in elder care and the various drug therapies available believe he is. I can only go by what I see and something hasn't been right about Biden for the last several years, including last Thursday night.
BTW, if Biden doesn't have early stage dementia and is not being given drugs to get him through things like the SOTU speech how do you explain these wide swings in demeanor? Is he just naturally unstable or are we dealing with some other issue? Because watching Biden's SOTU speech and then watching his interviews the next day is like watching two completely different people.
Because a liberal Democrat says so?
We must be near the truth.
No, it's on you to explain why he is Dr Jackal and Mr Hyde as you're voting for him and I am not.Ok if you want to believe that, that's fine. But if you really think that watching Biden on Thursday and watching him on Friday "is likely watching two completely different people," then it seems like it is on you to explain why. Adderall and other amphetamines would not cause noticeable cognitive changes on a day-to-day basis. That's the point. As for me, I disagree with the premise that there is a tremendous difference from one day to another so I am not searching for an explanation.
The skin is a lot more then a barrier. And let's back to my original off topic point: if you were gashed and bleeding while lost in the jungle and youTransdermal medications work by being absorbed through the skin. The skin is a barrier and meant to separate the external environment from living tissue, but it isn't impenetrable. No one is suggesting it is. That doesn't change the fact that things that are designed to act at the level of the non-living external skin layer are different from things designed to act on living tissue.
You are a liar. Quote what he said.The quote and video has been posted . Ignore it, make an excuse or forget it was said. Your prerogative.
It didn’t need to be altered to show you a liar. Quote EXACTLY what he said.Guess video was altered as usual
Why? U won't believe anyway.It didn’t need to be altered to show you a liar. Quote EXACTLY what he said.
Trump isn't jekyll and Hyde? Watch his prewritten speeches vs conversational speeches.No, it's on you to explain why he is Dr Jackal and Mr Hyde as you're voting for him and I am not.
I'm saying that the Adderall or whatever amphetamine cocktail Biden may have been on was used to mask his lost, listless behavior by converting his personality into that of an angry shouting crazy man. Then when the drugs were stopped the next day he reverted back to being a lost & listless speaker who forgets all sorts of things.
BTW, did you see Biden's SOTU speech and then his interviews the next day? There is no way you didn't see a big difference.
LMAO, still punching yourself in the face?Why? U won't believe anyway.
I know what he said. I heard it and read the transcript. You are a liar about what he said.Why? U won't believe anyway.
The skin is a lot more then a barrier. And let's back to my original off topic point: if you were gashed and bleeding while lost in the jungle and you
only had a bottle of Tequila to cleanse the wound before applying a bandage would you use the alcohol or not?
No, it's on you to explain why he is Dr Jackal and Mr Hyde as you're voting for him and I am not.
I'm saying that the Adderall or whatever amphetamine cocktail Biden may have been on was used to mask his lost, listless behavior by converting his personality into that of an angry shouting crazy man. Then when the drugs were stopped the next day he reverted back to being a lost & listless speaker who forgets all sorts of things.
BTW, did you see Biden's SOTU speech and then his interviews the next day? There is no way you didn't see a big difference.
The rational for shutting down the country and draconian mitigation did which was the point.no he was not right, covid did not disappear by april. imprecise and blustery is merely a excuse , the man is stupid.
It worked fine as the vast majority of the population was never at risk of serious illness. Spreading natural immunity is the best way to limit its potency.how can that be trump claimed it would disappear by april? well guess what society was open and normal when covid arrived how did that work? the only reason trump wanted the country open was because it was good for him.
Democrats.Who tried to overthrow the 2016 election?
Cannibals are an underrepresented demographic in America. Need to bring them here to do the job Americans won't do.How long before Biden invites thousands of angry, violent "newcomers" here from Haiti?