CoronaVirus

Virus update in Ohio
As of yesterday
April 29: 17,303 confirmed and probable cases with 937 deaths.

Totals today
Plus 724 cases (18,027)
Plus 38 deaths (975)
 
Remdesivir is a nucleotide analogue, in the same drug class as the HIV and hepatitis B medication Viread (tenofovir disoproxil fumarate) and the hepatitis C direct-acting antiviral Sovaldi (sofosbuvir), both also manufactured by Gilead. These drugs interfere with the viral polymerase enzyme (which in the case of HIV is known as reverse transcriptase), acting as defective building blocks that prevent a virus from copying its genetic material.

The results of a clinical trial of more than 1,000 people found that hospitalized COVID-19 patients with respiratory problems got better 31 percent faster than those who took a placebo, according to the National Institute of Allergy and Infectious Diseases.
But Pitts warned that the drug has shown to a benefit for only the sickest of the sick — hospitalized patients who are elderly, have respiratory problems or preexisting health trouble.
“It’s saving lives but it’s not a game-changer,” he said. “Clinical trials have shown it has led to recovery in 4 to 10 percent of this desperately ill population.”
He added, “85 percent of people with the virus will ride it out at home with fluids in bed; it’s not for them. This is not a drug for everyone.”
 
Did not want to start another virus thread not did I want to out this in one of the ones on the football forum.
A person who is involved in the Kentucky school system to me, that they have been told that they are making plans for the next school year, that includes teacher being in the school all five days but the students will be split into two groups. One group goes to school M/W/F/ and the other on T/Th.
If this is the plan they use I can't see fall sports there.
 
tom 48 said:
Remdesivir is a nucleotide analogue, in the same drug class as the HIV and hepatitis B medication Viread (tenofovir disoproxil fumarate) and the hepatitis C direct-acting antiviral Sovaldi (sofosbuvir), both also manufactured by Gilead. These drugs interfere with the viral polymerase enzyme (which in the case of HIV is known as reverse transcriptase), acting as defective building blocks that prevent a virus from copying its genetic material.

The results of a clinical trial of more than 1,000 people found that hospitalized COVID-19 patients with respiratory problems got better 31 percent faster than those who took a placebo, according to the National Institute of Allergy and Infectious Diseases.
But Pitts warned that the drug has shown to a benefit for only the sickest of the sick — hospitalized patients who are elderly, have respiratory problems or preexisting health trouble.
“It’s saving lives but it’s not a game-changer,” he said. “Clinical trials have shown it has led to recovery in 4 to 10 percent of this desperately ill population.”
He added, “85 percent of people with the virus will ride it out at home with fluids in bed; it’s not for them. This is not a drug for everyone.”
Click to expand...
www.poz.com

UPDATED: Remdesivir Shows Promise for COVID-19, but Not a Game Changer

FDA grants emergency use authorization, but randomized clinical trials of the antiviral drug show mixed results.
www.poz.com www.poz.com
 
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