Region 1: St. Ed's over Medina 45-42. This is going to be a shootout. Ed's can score, averaging over 40 a game. I don't think they will stop Allar and the Medina passing attack much either. Ed's seems to rise to the occasion in these types of games though and make the play to win it.
Region 2: Springfield over Marysville 17-13. Can't get a really good read on this game, but Springfield is the more talented team. Marysville hasn't played a difficult schedule, but they've been dominant.
Region 3: Pickerington Central over Upper Arlington 20-3. Just a huge talent disparity in this game, and I think PC dominates on both lines.
Region 4: Lakota West over Moeller 17-0. I worry about Lakota West's offense doing anything in a big game, but their defense is the best one I've seen in SWO since '07 St. X.