US Youth Soccer based leagues:
GCSL (formerly CUSL) - Provides league play for all ages, including U8s in Cincinnati area
MVYSA - Provides league play for all ages in Dayton area
MOSSL - Provides league play for all ages in Columbus area
Buckeye Premier League - Provides cross district play at U11 (sometimes U10) and up.
TPL - Provides high level play, mostly for U10-U13, stronger on girls side. Teams come from IN, KY, OH
OSSL - State League run by Ohio South, used as qualifier for Midwest Regional League
MRL - Midwest Regional League - Multiple levels of play, and geographic regions.
National League - Qualify through MRL, League play for top level USYSA based teams
Rec Leagues - Ohio South does sanction some recreational programs in Southern Ohio
SAY based leagues - Many rec programs are run by SAY (based in Cincinnati), but not all.
US Club based Leagues:
EPL - Run by Ohio Elite for younger teams
ECNL - Competitive national program, club based league. Only ECNL club in Cincinnati is Ohio Elite.
Ohio Champions League - Based in Columbus, competitor to Buckeye Premier